Cangrilintide

Cagrilintide | >99% Purity Long-Acting Amylin Analogue A synthetic, long-acting analogue of the endogenous pancreatic hormone amylin (islet amyloid polypeptide). Cagrilintide is widely recognized in scientific literature for its potent ability to regulate energy balance and induce satiety, offering a significantly extended half-life compared to native amylin.

Purity: >99% independently verified via HPLC/MS to ensure metabolic, glycemic, and obesity models remain precise and uncontaminated.
Action: Acts as a non-selective agonist at amylin and calcitonin receptors, modulating central satiety pathways in the brain (specifically the area postrema) to significantly reduce food intake and delay gastric emptying.
Research Focus: Investigated for robust weight management, glycemic control, and its highly synergistic effects when co-administered with GLP-1 receptor agonists (such as semaglutide).
The BioRegen Standard: Doctor-reviewed specifications and physically stocked in the USA for rapid laboratory delivery.

Strictly for laboratory and research purposes only.

$1.00

Cagrilintide Research-Grade Long-Acting Amylin Analogue

Product Overview

Cagrilintide is a potent, synthetic acylated analogue of the endogenous hormone amylin. Naturally secreted by pancreatic beta cells alongside insulin, amylin plays a critical role in postprandial glucose metabolism and satiation signaling.

In scientific literature, Cagrilintide is distinguished by its function as a non-selective Amylin Receptor Agonist (AMYR) and a Calcitonin Receptor Agonist. Unlike native amylin, which has a very short half-life, Cagrilintide is engineered with a fatty acid side chain that allows for strong albumin binding, significantly extending its biological activity. Its primary mechanism involves the dual modulation of homeostatic and hedonic food intake pathways in the hindbrain (specifically the area postrema). When studied in metabolic models, it has demonstrated a profound ability to delay gastric emptying and induce sustained reductions in caloric intake, making it a premier compound for research into obesity, glucose dysregulation, and synergistic weight-loss mechanisms.

Primary Research Applications

Under doctor-reviewed scientific literature, Cagrilintide is frequently utilized in in vitro and animal model studies to observe:

Satiety Pathway Activation: Investigating the modulation of anorexigenic signals in the central nervous system to reduce cumulative food intake.
Gastric Emptying Kinetics: Measuring the rate of nutrient absorption and its subsequent effect on postprandial glycemic excursions.
Synergistic Metabolic Research: Tracking the enhanced weight-loss efficacy when co-administered with GLP-1 receptor agonists (such as Semaglutide or Tirzepatide).
Glucagon Suppression: Observing the inhibition of inappropriate post-meal glucagon secretion, contributing to improved glucose homeostasis.

The BioRegen Standard

When you source your Cagrilintide from BioRegen Peptides, you are backed by our five core pillars of quality and service:

Uncompromising Purity: Every batch is independently third-party tested to guarantee >99% purity and molecular integrity, ensuring your metabolic research data is precise.
Doctor-Reviewed Accuracy: All product specifications and research handling guidelines are medically reviewed for absolute scientific accuracy.
Unbeatable Value: Premium, verified research compounds at industry-disrupting prices.
Fast, US-Based Shipping: Stocked physically in the USA to bypass customs delays and arrive at your lab in days.
Dedicated Support: Have a question about amylin receptor affinity? Email our US-based team at support@bioregenpeptides.com for a rapid response.

Product Specifications

Nomenclature: Cagrilintide
Mechanism: Long-acting Amylin Analogue (AMYR Agonist)
CAS Number: 1415456-99-3
Molecular Formula: $C_{180}H_{282}N_{50}O_{56}$
Purity: >99% (Verified via HPLC/MS)
Format: Lyophilized Powder

Regulatory Notice: This product is sold strictly for laboratory and research purposes only. It is not intended for human consumption, diagnostic, therapeutic, or prophylactic use. Please refer to our doctor-reviewed handling guidelines for proper research protocols.